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Eutylone and pentylone inhibited uptake at serotonin transporters (SERT), though dibutylone did not. Moreover, eutylone and pentylone shown weak partial releasing steps at SERT which achieved 50% of maximal response. All drugs stimulated dose-related locomotion in mice, and eutylone was most potent and efficacious Within this regard (ED50 = 2 mg/kg